Timothy K. Starr
This ebook; Cancer Driver Genes: Methods and Protocols (PDF) presents protocols for the identification of genetic drivers of cancer. Chapters guide readers through a brief history of cancer gene discovery; in vitro approaches; in silico approaches; and in vivo approaches using forward genetic screens in mice. Written in the highly successful Methods in Molecular Biology series format; chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step; readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge; Cancer Driver Genes: Methods and Protocols aims to provide protocols that will be used and adapted by cancer researchers to expand the knowledge base of molecular mechanisms contributing to the progression; initiation; and metastasis of cancer.