Tumors/cancers are described by uncontrolled growths of abnormal cells that spread beyond their usual boundaries and disturb the normal functions of affected organs and systems. Though about 75%–80% of tumors/cancers arise sporadically without a family connection; 20%–25% appear to be familial (counting 10%–15% nonhereditary familial tumors [or familial tumors] and 5%–10% hereditary familial tumors [or hereditary tumors]). As hereditary and nonhereditary familial tumors often demonstrate both tumor-related and non-tumor-related (or syndromic) symptoms; they are stated as tumor syndromes (or cancer susceptibility syndromes).
In comparison with irregular tumors/cancers; tumor syndromes (>300 described so far) tend to happen at a younger age; involve multiple organs and systems; produce numerous (often in a distinct spectrum) and bilateral lesions; form multiple hamartomatous; precursor or benign lesions; locate in the specific site(s); display exclusive syndromic features; and impact multiple members/generations of a family.
Handbook of Tumor Syndromes (PDF) provides authoritative and state-of-art coverage of about 100 tumor syndromes; with chapters presenting summaries of individual tumor syndromes in connection to their biology; epidemiology; clinical features; pathogenesis; diagnosis; treatment; and prognosis. Featuring contributions from clinicians; oncologists; and specialists; the ebook provides a reliable; comprehensive reference on tumor syndromes for students and scholars of medicine; dentistry; nursing; pharmacology; public health; and other biomedical disciplines.
- Includes expert coverage from renowned oncologists and clinicians
- Includes up-to-date information on the diagnosis and treatment of tumor syndromes
- Reviews the biology; pathogenesis; epidemiology; and clinical features of tumor syndromes
- S. T. Shanmugam; Understanding Cancer Therapies (ISBN 9781138198159)
- Liu; Tumors and Cancers: Endocrine Glands – Blood – Marrow – Lymph (ISBN 9781498729758)
- J. M. Baehring and J. M. Piepmeier; eds.; Brain Tumors: Practical Guide to Diagnosis and Treatment (ISBN 9780367390228)
- R. McIntosh; Understanding Cancer: An Introduction to the Biology; Medicine; and Societal Implications of This Disease (ISBN 9780815345350)
Dongyou Liu; Ph.D.; has worked at numerous research and clinical laboratories in Australia and the United States for the last three decades; with an emphasis on molecular characterization of microbial pathogens and recognition of human genetic disorders and tumors/cancers. He is the primary author of over 50 original review and research articles in various peer-reviewed international journals; the contributor of 197 book chapters; and the editor of over 10 ebooks.
NOTE: The product includes the ebook; Handbook of Tumor Syndromes in PDF. No access codes are included.
Table of contents
Table of contents :
1. Introductory Remarks. Section I: Tumor Syndromes Affecting the Brain, Head, and Lungs. 2. Aicardi syndrome and Klinefelter syndrome. 3. BAP1 Tumor predisposition syndrome. 4. Congenital central hypoventilation syndrome. 5. Familial neuroblastoma. 6. Pleuropulmonary blastoma. 7. Retinoblastoma. 8. Rhabdoid tumor predisposition syndrome. 9. Rubinstein-Taybi syndrome. 10. Schinzel-Giedion syndrome. 11. Schwannomatosis. 12. Von Hippel-Lindau syndrome. Section II: Tumor Syndromes Affecting the Digestive System. 13. Alagille syndrome. 14. Constitutional mismatch repair deficiency syndrome. 15. Cronkhite-Canada syndrome. 16. Familial adenomatous polyposis. 17. Familial gastrointestinal stromal tumor. 18. Hereditary diffuse gastric cancer. 19. Juvenile polyposis syndrome. 20. Lynch syndrome. 21. MUTYH-associated polyposis. 22. Peutz-Jeghers syndrome. 23. Serrated polyposis syndrome. 24. Tylosis with esophageal cancer. Section III: Tumor Syndromes Affecting the Urogenitory System. 25. Bardet-Biedl synndrome. 26. Birt-Hogg-Dubé syndrome. 27. Bohring-Opitz syndrome. 28. Familial testicular germ cell tumor. 29. Familial Wilms tumor and related syndromes. 30. Hereditary breast cancer and ovarian cancer. 31. Hereditary leiomyomatosis and renal cell cancer. 32. Hereditary papillary renal cell cancer. 33. Hereditary prostate cancer. 34. Microphthalmia-associated transcription family translocation renal cell cancer. 35. Mulibrey nanism. Section IV: Tumor Syndromes Affecting the Skin, Soft Tissue, and Bone. 36. Brooke-Spiegler syndrome. 37. Currarino syndrome. 38. Cutaneous malignant melanoma. 39. Familial atypical multiple mole melanoma syndrome. 40. Familial chordoma. 41. Hereditary multiple osteochondromas. 42. Karatitis-Ichthyosis-Deafness syndrome. 43. Li-Fraumeni syndrome. 44. McCune-Albright syndrome. 45. Milroy disease. 46. Mosaic variegated aneuploidy syndrome. 47. Roberts syndrome. 48. Rothmund-Thompson syndrome. 49. Werner syndrome. 50. Xeroderma pigmentosum. Section V: Tumor Syndromes Affecting the Endocrine System. 51. Carney complex. 52. Congenital adrenal hyperplasia. 53. Familial hyperparathyroidism. 54. Familial isolated pituitary adenoma. 55. Familial non-medullary thyroid carcinoma. 56. Familial pancreatic cancer. 57. Hereditary pancreatitis. 58. Hereditary pheochromocytoma and paraganglioma syndrome. 59. Mahvash disease. 59. Multiple endocrine neoplasia. 60. Pendred syndrome. Section VI: Tumor Syndromes Affecting the Hematopoietic and Lymphoreticular Systems. 62. Ataxia-telangiectasia syndrome. 63. Autoimmune lymphoproliferative syndrome. 64. Bloom syndrome. 65. Chediak-Higashi syndrome. 66. Congenital amegakaryocytic thrombocytopenia. 67. Diamond-Blackfan anemia. 68. Down syndrome. 69. Dyskeratosis congenita. 70. Familial acute myeloid leukemia. 71. Familial monosomy 7 syndrome. 72. Familial multiple myeloma. 73. Fanconi anemia. 74. GATA2 Deficiency. 75. LPD Associated with Epstein-Barr virus infection. 76. Nijmegen breakage syndrome. 77. Severe congenital neutropenia. 78. Shwachman-Diamond syndrome. 79. Sjögren syndrome. 80. SRP72-Associated bone marrow failure syndrome. 81. Thrombocytopenia-absent radius. 82. Waldenström macroglobulinemia. Section VII: Overgrowth Syndromes, PTENopathies, and RASopathies. 84. Bannayan-Riley-Ruvalcaba syndrome. 85. Basal cell nevus syndrome. 86. Beckwith-Wiedemann syndrome. 87. CBL Syndrome. 88. CLOVES Syndrome. 89. Costello syndrome. 90. Cowden syndrome. 91. Klippel-Trenaunay syndrome. 92. Neurofibromatosis typese 1 and 2. 93. Noonan syndrome. 94. Perlman syndrome. 95. Proteus syndrome. 96. Schimmelpennning-Feuerstein-Mims syndrome. 97. Simpson-Golabi-Behmel syndrome. 98. Sotos syndrome. 99. Tuberous sclerosis complex. 100. Weaver syndrome.