The Human Mitochondrial Genome: From Basic Biology to Disease

Download The Human Mitochondrial Genome: From Basic Biology to Disease written by Giuseppe Gasparre, Anna Maria Porcelli in PDF format. This book is under the category Genetics and bearing the isbn/isbn13 number 128196564/9780128196564. You may reffer the table below for additional details of the book.


SKU: 7c4bf50b7155 Category: Tag:



Giuseppe Gasparre, Anna Maria Porcelli


Academic Press




596 pages









Book Description

The Human Mitochondrial Genome: From Basic Biology to Disease is a comprehensive and up-to-date assessment of human mitochondrial genomics, integrating basic research to translational medicine across a variety of disease types. It is available as a PDF document. In this article, scientists from all over the world explain the fundamental aspects of the biology of human mitochondrial DNA (mtDNA), such as its maintenance and repair, as well as its inheritance and segregation. In addition, topics such as the development and utilization of mtDNA, mutations, models, and methodologies for research on the functional aspects of mtDNA are discussed. Cancer, age-related diseases, mtDNA depletion, neurodegenerative diseases, deletion diseases, and point mutation diseases are some of the disease categories that are covered in the topic of disease, which is reinforced with attempts for therapeutic options. Among the treatment strategies that have been investigated in depth are nucleosides supplementation, mitoZNF nucleases, and mitoTALENs nucleases.

As funding for research on mtDNA continues to increase, a growing number of doctors, scientists, and clinicians are focusing their attention on the relationship of mtDNA with disease. This ebook gives the tools and background information essential to do novel and effective research in this exciting space. Whether your goal is to distinguish a disease-related mutation or a haplogroup-defining variant, or to discover developing treatment pathways, this ebook has you covered.


  • Describes and analyzes important research processes and points of view that younger scientists should learn.
  • Includes a team of authors from all around the world who are considered to be experts in their fields, ranging from basic biologists to clinician-scientists.
  • Discussion of the disease, along with diagnostic and treatment approaches that are now being used in clinical practice
  • Comprehensive analysis of recent scientific discoveries and technology improvements made in the field; paves the way for future mtDNA investigations; identifies variants and mutations; conducts pathogenic analysis; and details therapeutic options.



PLEASE TAKE NOTE That the only thing that is included in the purchase is the PDF version of the book “The Human Mitochondrial Genome: From Basic Biology to Disease.” There are no access codes contained within.


There are no reviews yet.

Be the first to review “The Human Mitochondrial Genome: From Basic Biology to Disease”

Recent Posts

Blogging And How You Can Get A Lot From It

Whether you’re just looking to type about a hobby you have or if you want to attempt to run a business, starting a blog might be worthy of your consideration. Before you get started, first take a few minutes to read these expert-provided tips below. Once you learn about blogging,…

5 tips for a good business blog

Follow my blog with BloglovinAre you also looking for a good structure for your business blogs? That you finally have a serious and good structure for all your texts that are online? On your website but also on social media. In this review you will find 5 tips from Susanna Florie from her…

Study tips from a budding engineer

“Why engineering?” is a question I get often. The answer for me is simple: I like to solve problems. Engineering is a popular field for many reasons. Perhaps this is because almost everything around us is created by engineers in one way or another, and there are always new, emerging and exciting technologies impacting…

How do I study mathematics and pass my exam?

Not sure how best to study math ? Are you perhaps someone who starts studying the day before the exam? Then you know yourself that your situation is not the most ideal. Unfortunately, there is no magic bullet to make you a maths crack or pass your exam in no time . It is important to know that mathematics always builds on…