Michael B. Smith
Organic chemists can use the Compendium of Organic Synthetic Methods (PDF) as a quick desktop reference to browse new reactions and transformations of interest. This makes it easier for organic chemists to look for functional group transformations in the original literature of organic chemistry. The functional group transformations and carbon-carbon bond generating reactions that were published in the scientific literature between 2005 and 2008 are included in Volume 13. It provides illustrations of previously known procedures for the production of compounds with a single function.
The following are some of the many topics that are discussed in Volume 13:
- Alcohols, in addition to Thiols
- Sulfonates as well as Halides
- Compounds With Dual Purposes
- Alkyls, Methylenes, and Aryls are the following:
- Epoxides, Ethers, and Thioethers are the following:
- Carboxylic Acids; Esters and Amides
The Compendium of Organic Synthetic Methods series makes it easier to find quality; selected functional group transformations; an organization that is based on the reaction between a functional group of starting material and a functional group generated; and complete references to each reaction. This article presents some examples of reported reactions for the production of monofunctional compounds based on research published between 2005 and 2008. A working organic chemist will find this to be a helpful reference as well as an invaluable tool because it enables a speedy check of known organic transformations. stringent criteria for the inclusion of reactions, including the actual synthetic utility of reactions; reagents that are readily available or easily synthesized and handled in the laboratory; and
The Compendium of Organic Synthetic Methods, Volume 13, updates the more than 18 thousand examples included in Volumes 1–12 by including around 2,500 instances of reported reactions for the creation of monofunctional compounds. In addition to this, it includes around one thousand examples of reactions for creating difunctional compounds within a variety of functional groups; this represents an update to the more than ten thousand examples presented in Volumes 1–12. This volume adds 99 relevant reviews, which have been a staple of this series for quite some time, and places them in a variety of topics. After chapter 16, there is a helpful alphabetical list of all the authors who were cited.
In order to facilitate speedy information retrieval and reference, the organizational scheme classifies chemical transformations first according to the reaction of the functional group of the starting material, and then according to the functional group that is formed as a result of the transformation. In addition, indices for monofunctional and difunctional molecules lead the user to certain classes of transformations in an effective and efficient manner.
For the practicing chemist as well as the student, Compendium of Organic Synthetic Methods, Volume 13 offers a highly focused source of information on the methods, reactions, and transformations in contemporary organic chemistry.