Handbook of Basal Ganglia Structure and Function (2nd Edition)

Download Handbook of Basal Ganglia Structure and Function (2nd Edition) written by Heinz Steiner, Kuei Y. Tseng in PDF format. This book is under the category Medicine and bearing the isbn/isbn13 number 012802206X/9780128022061. You may reffer the table below for additional details of the book.


SKU: d3157f2f0212 Category: Tag:



Heinz Steiner, Kuei Y. Tseng


Academic Press; 2nd edition




1036 pages









Book Description

The Second Edition of the Handbook of the Structure and Function of the Basal Ganglia; (PDF) provides a comprehensive overview of the anatomical and functional characteristics of the basal ganglia, with an emphasis on the therapeutic importance of these elements. The basal ganglia are a set of forebrain nuclei that are associated with the cerebral cortex, the thalamus, and the brainstem. They are required for several activities of the brain, including sensory integration, motor control, learning, and cognition.

These nuclei are necessary for normal brain function and behavior, and their significance is further emphasized by the numerous and varied disorders that are associated with basal ganglia dysfunction. Some examples of these disorders include Parkinson’s disease, Huntington’s disease, Tourette’s syndrome, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. In addition, these nuclei are essential for the maintenance of normal brain structure.

This second edition that has been updated has undergone extensive revisions so that it can provide the most up-to-date account possible of this important brain region. The new edition has ten entirely new chapters that provide expanded coverage of anatomy and physiology; detailed accounts of latest advances in cellular/molecular mechanisms and cellular/physiological mechanisms; and significant, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction. The editors and authors of the new edition are internationally acclaimed basal ganglia researchers.

The purpose of this article is to synthesize information from a wide variety of sources regarding the behavioral neurobiology of the basal ganglia. This information includes cellular/molecular and cellular/physiological mechanisms, advancements in the understanding of anatomy, as well as behavioral and clinical aspects of function and dysfunction.



  • Written by authors from all over the world who are recognized as leading experts in their fields
  • examines in depth the therapeutically significant effect that the basal ganglia have on a number of different neurological and psychiatric conditions



PLEASE TAKE NOTE That the product comes with a PDF version of the booklet “Handbook of Basal Ganglia Structure and Function, 2e.” There are no access codes contained within.

Table of contents

Handbook of Basal Ganglia Structure and Function Page i
Handbook of Basal Ganglia Structure and Function Page iii
Copyright Page iv
Dedication Page v
Contents Pages vii-xiv
List of Contributors Pages xv-xviii
Preface Pages xix-xx
Acknowledgments Page xxi
List of Abbreviations Page xxiii
Chapter 1 – The Neuroanatomical Organization of the Basal Ganglia Pages 3-32 C.R. Gerfen, J.P. Bolam
Chapter 2 – The History of the Basal Ganglia: The Nuclei Pages 33-44 A. Parent
Chapter 3 – The History of the Basal Ganglia: Cells and Circuits Pages 45-62 C.J. Wilson
Chapter 4 – The Conservative Evolution of the Vertebrate Basal Ganglia Pages 63-97 A. Reiner
Chapter 5 – Cell Types in the Different Nuclei of the Basal Ganglia Pages 99-117 D.E. Oorschot
Chapter 6 – The Striatal Skeleton: Medium Spiny Projection Neurons and Their Lateral Connections Pages 121-136 D. Plenz, J.R. Wickens
Chapter 7 – The Cholinergic Interneuron of the Striatum Pages 137-155 J.A. Goldberg, C.J. Wilson
Chapter 8 – GABAergic Interneurons of the Striatum Pages 157-178 J.M. Tepper, T. Koós
Chapter 9 – Dopaminergic Modulation of Glutamatergic Signaling in Striatal Spiny Projection Neurons Pages 179-196 W. Shen, J.L. Plokin, S. Zhai, D.J. Surmeier
Chapter 10 – Endocannabinoid Signaling in the Striatum Pages 197-215 D.M. Lovinger, B.N. Mathur
Chapter 11 – Nitric Oxide Signaling in the Striatum Pages 217-236 A.R. West
Chapter 12 – Role of Adenosine in the Basal Ganglia Pages 237-256 M. Morelli, N. Simola, P. Popoli, A.R. Carta
Chapter 13 – Organization of the Globus Pallidus Pages 259-276 H. Kita, D. Jaeger
Chapter 14 – The Subthalamic Nucleus Pages 277-291 M.D. Bevan
Chapter 15 – The Substantia Nigra Pars Reticulata Pages 293-316 F.M. Zhou
Chapter 16 – Subtypes of Midbrain Dopamine Neurons Pages 317-334 M. Subramaniam, J. Roeper
Chapter 17 – Neurophysiology of Substantia Nigra Dopamine Neurons: Modulation by GABA and Glutamate Pages 335-359 C.A. Paladini, J.M. Tepper
Chapter 18 – Plasticity in Dopamine Neurons Pages 361-372 S.A. Quraishi, C.A. Paladini
Chapter 19 – Regulation of Extracellular Dopamine: Release and Uptake Pages 373-402 D. Sulzer, S.J. Cragg, M.E. Rice
Chapter 20 – Organization of Corticostriatal Projection Neuron Types Pages 405-422 A. Reiner, Y. Deng
Chapter 21 – Organization of Prefrontal-Striatal Connections Pages 423-438 H.J. Groenewegen, F.G. Wouterlood, H.B.M. Uylings
Chapter 22 – Gating of Cortical Input Through the Striatum Pages 439-457 M.G. Murer, P. O’Donnell
Chapter 23 – Regulation of Corticostriatal Synaptic Plasticity in Physiological and Pathological Conditions Pages 459-476 M. Di Filippo, P. Calabresi
Chapter 24 – The Thalamostriatal Systems in Normal and Disease States Pages 477-493 A. Galvan, R.M. Villalba, T. Wichmann, Y. Smith
Chapter 25 – The Tail of the Ventral Tegmental Area/Rostromedial Tegmental Nucleus: A Modulator of Midbrain Dopamine Systems Pages 495-511 M. Barrot, F. Georges, P. Veinante
Chapter 26 – The Rostromedial Tegmental Nucleus: Connections With the Basal Ganglia Pages 513-534 D.S. Zahm
Chapter 27 – Integrative Networks Across Basal Ganglia Circuits Pages 535-552 S.N. Haber
Chapter 28 – Receptors and Second Messengers in the Basal Ganglia Pages 555-581 E.B. Warren, S.E. Sillivan, C. Konradi
Chapter 29 – Regulation of Striatal Signaling by Protein Phosphatases Pages 583-607 J.-A. Girault, P. Greengard, A.C. Nairn
Chapter 30 – Neurotransmitter Regulation of Striatal Gene Expression Pages 609-637 K.A. Keefe, K.A. Horner
Chapter 31 – Psychostimulant-Induced Gene Regulation in Striatal Circuits Pages 639-672 H. Steiner
Chapter 32 – Epigenetics in Neuropathologies of the Basal Ganglia Pages 673-685 J. Caboche, K. Brami-Cherrier, E. Roze
Chapter 33 – Investigating Basal Ganglia Function With Cell-Type-Specific Manipulations Pages 689-706 A.V. Kravitz, K. Devarakonda, A.C. Kreitzer
Chapter 34 – Phasic Dopamine Signaling in Action Selection and Reinforcement Learning Pages 707-723 P. Redgrave, N. Vautrelle, P.G. Overton, J. Reynolds
Chapter 35 – Memory Systems of the Basal Ganglia Pages 725-740 J. Goodman, M.G. Packard
Chapter 36 – Abnormal Activities in Cortico-Basal Ganglia Circuits in Movement Disorders Pages 741-754 J.R. Walters
Chapter 37 – Morphological Plasticity in the Striatum Associated With Dopamine Dysfunction Pages 755-770 R. Moratalla, O. Solís, L.M. Suárez
Chapter 38 – Neuroinflammation in Movement Disorders Pages 771-782 E. Saavedra-López, P.V. Casanova, G.P. Cribaro, C. Barcia
Chapter 39 – Disease-Associated Changes in the Striosome and Matrix Compartments of the Dorsal Striatum Pages 783-802 J.R. Crittenden, A.M. Graybiel
Chapter 40 – Etiology and Progression of Parkinson’s Disease: Cross-Talk Between Environmental Factors and Genetic Vulnerability Pages 803-819 P.O. Fernagut
Chapter 41 – Determinants of Selective Vulnerability of Dopamine Neurons in Parkinson’s Disease Pages 821-837 E. Zampese, D.J. Galtieri, P.T. Schumacker, D.J. Surmeier
Chapter 42 – Parkinson’s Disease: Genetics Pages 839-855 A. Mamais, M.R. Cookson
Chapter 43 – Molecular Mechanisms of l-DOPA-Induced Dyskinesia Pages 857-871 M.A. Cenci
Chapter 44 – Cell Therapy in Parkinson’s Disease: Understanding the Challenge Pages 873-888 K. Steece-Collier, T.J. Collier
Chapter 45 – Cellular and Molecular Mechanisms of Neuronal Dysfunction in Huntington’s Disease Pages 889-906 J. Caboche, P. Vanhoutte, L. Boussicault, E. Roze, S. Betuing
Chapter 46 – Alterations of Synaptic Function in Huntington’s Disease Pages 907-927 A. Parievsky, C. Cepeda, M.S. Levine
Chapter 47 – Pathophysiology of Dystonia Pages 929-950 G. Madeo, A. Pisani
Chapter 48 – Tourette Syndrome and Tic Disorders Pages 951-970 L. Tochen, H.S. Singer
Chapter 49 – Deep-Brain Stimulation for Neurologic and Neuropsychiatric Disorders Pages 971-995 T. Wichmann
Index Pages 997-1012


There are no reviews yet.

Be the first to review “Handbook of Basal Ganglia Structure and Function (2nd Edition)”

Recent Posts

Blogging And How You Can Get A Lot From It

Whether you’re just looking to type about a hobby you have or if you want to attempt to run a business, starting a blog might be worthy of your consideration. Before you get started, first take a few minutes to read these expert-provided tips below. Once you learn about blogging,…

5 tips for a good business blog

Follow my blog with BloglovinAre you also looking for a good structure for your business blogs? That you finally have a serious and good structure for all your texts that are online? On your website but also on social media. In this review you will find 5 tips from Susanna Florie from her…

Study tips from a budding engineer

“Why engineering?” is a question I get often. The answer for me is simple: I like to solve problems. Engineering is a popular field for many reasons. Perhaps this is because almost everything around us is created by engineers in one way or another, and there are always new, emerging and exciting technologies impacting…

How do I study mathematics and pass my exam?

Not sure how best to study math ? Are you perhaps someone who starts studying the day before the exam? Then you know yourself that your situation is not the most ideal. Unfortunately, there is no magic bullet to make you a maths crack or pass your exam in no time . It is important to know that mathematics always builds on…