Computational Systems Pharmacology and Toxicology

Download Computational Systems Pharmacology and Toxicology written by Rudy J. Richardson, Dale E. Johnson, Noffisat Oki, David Faulkner, Carlos A. Rodriguez, Eugene V Radchenko in PDF format. This book is under the category Medicine and bearing the isbn/isbn13 number 1782623329/9781782623328. You may reffer the table below for additional details of the book.

$19.99

SKU: c24fe9f765a4 Category: Tag:

Specifications

book-author

Rudy J. Richardson, Dale E. Johnson, Noffisat Oki, David Faulkner, Carlos A. Rodriguez, Eugene V Radchenko

publisher

Royal Society of Chemistry; 1st edition

file-type

PDF

pages

349 pages

language

English

asin

B072MPTGMY

isbn10

1782623329

isbn13

9781782623328


Book Description

The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. In Computational Systems Pharmacology and Toxicology (PDF); computational approaches have the potential to improve toxicological experimental design; reduce the number of animals used in experimentation and also enable more rapid drug efficacy and safety testing. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment.
This PDF ebook provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures; toxicity-related databases; in silico chemical-protein docking; and biological pathway tools. The ebook begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The 2nd part of the ebook covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics.

This ebook will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.

 

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