Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging

Download Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging written by Johng S. Rhim, Anatoly Dritschilo, Richard Kremer in PDF format. This book is under the category Biology and bearing the isbn/isbn13 number 3030222535;3030222543; 303022256X/9783030222536/ 9783030222543/ 9783030222567. You may reffer the table below for additional details of the book.


SKU: 878d5691c824 Category: Tags: , ,



Johng S. Rhim, Anatoly Dritschilo, Richard Kremer


Springer; 1st ed. 2019 edition










3030222535;3030222543; 303022256X


9783030222536/ 9783030222543/ 9783030222567

Book Description

The book “Human Cell Transformation” (PDF), which is partly a contributed volume and partly a proceedings book, contains discussions on the most recent developments in cell models for the study of aging and cancer including human cells that have undergone transformation. The Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference, which took place in June 2018 at McGill University, contributed a significant number of chapters to this volume. The writers present global expertise on a wide variety of topics ranging from the various types of cancer (prostate, breast, bone, etc.) to the tumor microenvironment; homogeneity; tumor development; and possible therapies and treatments. The authors also discuss possible treatments and therapies.

PLEASE TAKE NOTE That the only component of this product is the downloadable ebook titled “Human Cell Transformation in PDF.” There are no access codes contained within.

Table of contents

Table of contents :
Front Matter ….Pages i-xiv
Front Matter ….Pages 1-1
Mechanisms Underlying Metastatic Pancreatic Cancer (Jason R. Pitarresi, Anil K. Rustgi)….Pages 3-10
Current Perspectives on Nasopharyngeal Carcinoma (Hui Mei Lee, Kazuhida Shaun Okuda, Fermín E. González, Vyomesh Patel)….Pages 11-34
An In Vitro Model of Triple-Negative Breast Cancer (J. Russo, Y. Su)….Pages 35-46
Emerging Role of Novel Biomarkers of Ly6 Gene Family in Pan Cancer (Geeta Upadhyay)….Pages 47-61
The Oncoprotein Gankyrin/PSMD10 as a Target of Cancer Therapy (Jun Fujita, Toshiharu Sakurai)….Pages 63-71
Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis (Byoung-Joon Song, Mohamed A. Abdelmegeed, Young-Eun Cho, Mohammed Akbar, Johng S. Rhim, Min-Kyung Song et al.)….Pages 73-87
Front Matter ….Pages 89-89
Novel Human Prostate Epithelial Cell Cultures (Johng S. Rhim)….Pages 91-99
African-American Prostate Normal and Cancer Cells for Health Disparities Research (Nicole Nicolas, Geeta Upadhyay, Alfredo Velena, Bhaskar Kallakury, Johng S. Rhim, Anatoly Dritschilo et al.)….Pages 101-108
Assessing the Advantages, Limitations and Potential of Human Primary Prostate Epithelial Cells as a Pre-clinical Model for Prostate Cancer Research (Fiona M. Frame, Amanda R. Noble, Peter O’Toole, Jo Marrison, Timothy Godden, Andrew O’Brien et al.)….Pages 109-118
Role of Alternative Splicing in Prostate Cancer Aggressiveness and Drug Resistance in African Americans (Jacqueline Olender, Norman H. Lee)….Pages 119-139
Discovery of Metabolic Biomarkers Predicting Radiation Therapy Late Effects in Prostate Cancer Patients (Amrita K. Cheema, Scott Grindrod, Xiaogang Zhong, Shreyans Jain, Smrithi S. Menon, Khyati Y. Mehta et al.)….Pages 141-150
Front Matter ….Pages 151-151
The Aging Skeleton (David Goltzman)….Pages 153-160
Parathyroid Hormone-Related Protein (PTHrP): An Emerging Target in Cancer Progression and Metastasis (Rui Zhang, Jiarong Li, Gloria Assaker, Anne Camirand, Siham Sabri, Andrew C. Karaplis et al.)….Pages 161-178
Targeting DNA Hypomethylation in Malignancy by Epigenetic Therapies (Niaz Mahmood, Shafaat A. Rabbani)….Pages 179-196
Front Matter ….Pages 197-197
Tumor Dormancy and Slow-Cycling Cancer Cells (John E. Davis Jr, Jason Kirk, Yibing Ji, Dean G. Tang)….Pages 199-206
Resolution of Cellular Heterogeneity in Human Prostate Cancers: Implications for Diagnosis and Treatment (Norman J. Maitland, Fiona M. Frame, Jayant K. Rane, Holger H. Erb, John R. Packer, Leanne K. Archer et al.)….Pages 207-224
Small Molecule Inhibition of Glycogen Synthase Kinase-3 in Cancer Immunotherapy (Alison Taylor, Christopher E. Rudd)….Pages 225-233
Back Matter ….Pages 235-244

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